New insights into how patient factors and COVID-19 infection affect antibody responses in people with HIV

People with HIV have impaired immune responses to some pathogens and immunizations, and during the COVID-19 pandemic, they often experienced severe symptoms if infected with SARS‐CoV‐2. New research led by investigators at Massachusetts General Hospital (MGH) has examined how patient characteristics and COVID-19 infection may affect the antibody responses of people with HIV—including antibody responses against SARS-CoV-2 proteins as well as proteins from other viruses such as cytomegalovirus (CMV) and Epstein-Barr Virus (EBV).