Researchers identify the origin of subset of autoantibodies that worsen lupus

In an effort to understand the origin of systemic lupus erythematosus and why some patients present with more severe disease than others, Johns Hopkins Medicine researchers say they have identified a type of autoantibody that may worsen the condition and have also found how these autoantibodies originate. They say their findings have implications for biomarker testing in lupus and may help identify patients that need early and aggressive treatment.

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