Transcriptomic changes in glia linked to specific neurodegenerative diseases

Neurodegenerative disorders such as Alzheimer, Parkinson and Huntington disease each cause their own distinct set of symptoms, yet they share a common feature: abnormal protein aggregation. It’s been unknown if overlapping cellular pathways underly the damaging accumulation of proteins in these diseases. Mounting evidence demonstrates how glial cells such as astrocytes and microglia play a key part in neurodegenerative disease.

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