Novel regulatory mechanism of blood clotting discovered

Hemostasis is vital to prevent excessive blood loss. However, there is an increased risk for thrombosis if there is an excessive reaction and uncontrolled formation of fibrin. In a new study published in Nature Cardiovascular Research, a research group from Würzburg led by Bernhard Nieswandt have uncovered platelet glycoprotein GPV as a central regulator for hemostasis and thrombus formation, a finding that opens the way to new therapeutic approaches.