In vitro 3D-engineered heart tissue that monitors drug-induced cardiotoxicity

Cardiotoxicity is a clinical condition that arises from using pharmaceutical agents such as antibiotics, which result in harmful effects on the heart, ultimately compromising its functional capacity. The left ventricle’s contractile ability is impaired, potentially leading to heart failure, a severe clinical outcome. Recently, a joint team of researchers from POSTECH and Georgia Institute of Technology successfully created an engineered heart via 3D printing technology that allows for early monitoring of drug-induced cardiotoxicity.

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