People with NAFLD may have decreased expression of a liver enzyme needed for medication processing

People with non-alcoholic fatty liver disease (NAFLD) may process certain medications less effectively due to significantly decreased levels of an important enzyme, according to a new study from Indiana University School of Medicine. A team of researchers led by Nick Powell, PharmD, and Naga Chalasani, MD, published their findings in the article “Clinically important alterations in pharmacogene expression in histologically severe nonalcoholic fatty liver disease” in the journal Nature Communications in March.