Guidance on clinical management of CHEK2 pathogenic variants and cancer risks

An international workgroup of genetics and cancer experts convened by the American College of Medical Genetics and Genomics (ACMG) has published a highly anticipated and detailed clinical practice resource on CHEK2 pathogenic variants: “Management of Individuals with Germline Pathogenic/Likely Pathogenic Variants in CHEK2: a Clinical Practice Resource of the American College of Medical Genetics and Genomics.”