Cardiac reparative and immune regulatory role of hPSC-derived epicardial cells uncovered for infarcted hearts

Recently, research groups led by Prof. Yang Huangtian from Shanghai Institute of Nutrition and Health (SINH) of the Chinese Academy of Sciences (CAS) and collaborator Prof. Gao Ling from Shanghai East Hospital of Tongji University found that intramyocardial injection of human embryonic stem cell-derived epicardial cells (hEPs) at the acute phase of myocardial infarction (MI) ameliorates functional worsening and scar formation in mouse and swine hearts.