Unbiased omics method finds in vivo host restriction factors for HIV-1

Research led by the Walter Reed Army Institute of Research, Maryland, has confirmed previous research findings of host restriction factors that target HIV-1. In a paper, “Single-cell transcriptomics identifies prothymosin α restriction of HIV-1 in vivo,” published in Science Translational Medicine, the authors detail how omics can uncover correlations in the search for cure strategies.