Revealing the roles of TLR7, a nucleic acid sensor for COVID-19, in pan-cancer

Researchers have discovered toll-like receptor 7 (TLR7), a nucleic acid sensor within the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus, to be aberrantly expressed in many types of cancers. However, its expression pattern across cancers and association with COVID-19 (or its causing virus SARS-CoV-2) has not been systematically studied.