Understanding mechanisms of alcohol-associated bowel disease

Alcohol consumption is a significant risk factor for gastrointestinal diseases, including cancer. Alcohol can damage the gastrointestinal tract in several ways. It can promote an impairment of several intestinal barrier functions, leading to leaky gut and dysbiosis. Ethanol metabolism can also produce toxic substances such as acetaldehyde and acetate, further damaging the gut and potentially promoting cancer.

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