Hot flashes are one of the most concerning and most reported symptoms among menopausal women and breast cancer survivors. Currently, paroxetine is a FDA-approved non-hormonal drug used for the treatment of hot flashes. In an article published this month in the journal Frontiers in Psychiatry, researchers at Baylor University tested the efficacy of paroxetine by conducting a systematic review and meta-analysis of six clinical trials, finding that the benefits of paroxetine in the treatment of hot flashes to be comparable to that of the placebo response.
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