Changing dosing methods means fewer mice needed to study lung infections

Researchers will need fewer mice to study lung infections thanks to improvements in dosing methods, according to a new study from the University of California San Francisco (UCSF). Changing how animals are anesthetized and infected with microbes allows scientists to study lung infections using smaller group sizes and without having to use invasive dosing methods. The study is published in the American Journal of Physiology-Lung Cellular and Molecular Physiology.