Metformin cuts insulin resistance and chances of kidney disease in young, obese rats

Improving insulin resistance with metformin, a medication used to treat type 2 diabetes, reduced the chances of developing kidney disease in a prepubescent obese rat model, according to a new study from the University of Mississippi Medical Center. Treatment with metformin also reduced early signs of inflammation and dyslipidemia (imbalance of fats such as cholesterol and triglycerides).