Major depressive disorder study finds differences between male and female brain processes at molecular level

Research published in Neuropsychopharmacology by a team of researchers at the University of Wollongong (UOW), National Institute of Complementary Medicine Health Research Institute and Neuroscience Research Australia has found molecular evidence highlighting important sex differences in the brains of people with major depressive disorder, with evidence of changes occurring specifically in the female brain, but not in males. The paper is titled “Sex- and suicide-specific alterations in the kynurenine pathway in the anterior cingulate cortex in major depression.”