Study links gene network and pancreatic beta cell defects to type 2 diabetes

A comprehensive study that integrates multiple analytic approaches has linked a regulatory gene network and functional defects in insulin-producing pancreatic beta cells to type 2 diabetes. The study, published Nov. 8 in the journal Nature, lays the foundation for identifying additional early disease-driving events for type 2 diabetes, and it also provides a template for identifying regulatory networks that drive other diseases.