Virologic rebound observed in 20% of patients treated with nirmatrelvir-ritonavir

An observational study of patients being treated for acute COVID-19 in a multicenter health care system observed virologic rebound in about 20% of patients treated with nirmatrelvir-ritonavir (N-R) versus about 2% of those who did not receive treatment. The findings are published in Annals of Internal Medicine.

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