Imaging breakthroughs provide insight into the dynamic architectures of HIV proteins

The human immunodeficiency virus (HIV) is a formidable pathogen. It mutates rapidly; in fact, estimates suggest that the genetic diversity of HIV in a single person at one point in time is equal to the diversity of influenza across the globe for a year. HIV also has developed structures to shield itself from recognition and attack by antibodies and therapeutics. These factors all contribute to HIV being a dangerous, hard-to-treat virus.

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