Use of GLP-1 receptor agonists to treat substance and alcohol use disorders is promising, but premature, say researchers

Semaglutide, a glucagon-like peptide-1 receptor agonist (GLP-1RA) originally formulated to treat diabetes, has gained traction as the latest and greatest weight loss drug. Among the hype, anecdotal observations from patients and providers alike have suggested the drug may also play a role in treating alcohol use disorder and other substance use disorders.