New 3D co-cultured model to study effect of proton therapy on aggressive brain cancer

Researchers at TU Delft designed novel 3D-engineered scaffolds inspired by the geometry of the brain microvasculature. The micro-structures were co-cultured with both glioblastoma, an aggressive brain cancer, and endothelial cells, the building blocks of blood vessels. This model enabled researchers to study the effect of proton therapy on glioblastoma and uncover a possible protective role of endothelial cells on cancer cells.