Revolutionizing probiotic therapy: The emergence of CRISPR-Cas engineered strains

Probiotics, defined as live microorganisms beneficial to health, have shown promise in areas like anti-inflammatory activity and brain function, etc. However, challenges remain due to variability in tolerance and colonization among species and strains. Recent advances in genome engineering, including CRISPR-Cas, have facilitated the creation of novel probiotic strains, offering potential treatments for metabolic disorders, inflammation, infections, and cancer.

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