Myeloid mutations associated with high-risk adult acute lymphoblastic leukemia

Scientists previously thought mutations in myeloid genes could only cause myeloid cancers such as myelodysplastic syndrome (MDS) or acute myeloid leukemia (AML)—hence the name given to these genes. However, a recent study led by researchers at the University of Chicago Medicine reveals that myeloid mutations can also cause high-risk acute lymphoblastic leukemia (ALL) and that ALL patients with these mutations require non-standard treatment.