Predictive model of oxaliplatin-induced liver injury based on artificial neural network and logistic regression

Since 2004, several clinical studies have reported that patients with OXA frequently experienced adverse effects of liver injury (LI), typically characterized by hepatic sinusoidal injury, splenomegaly, decreased platelet count, and noncirrhotic portal hypertension, which can progress to nodular regenerative hyperplasia with long-term treatment.

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