Substudy of trial reveals how statin therapy prevents cardiovascular disease in people with HIV

A recent clinical trial reveals how a daily statin pill may prevent heart attacks and strokes in people with HIV. In this substudy of the phase 3 Randomized Trial to Prevent Vascular Events in HIV (REPRIEVE), a team led by investigators at Massachusetts General Hospital (MGH) discovered that pitavastatin reduces plaque buildup in the heart’s coronary arteries and lowers inflammation in the blood. The findings are published in JAMA Cardiology.