Review highlights the potential and promise of CAR-T cell therapy in autoimmune diseases

Autoimmune disease (AID) refers to the condition in which the immune system identifies the body’s own cells and tissues as foreign, resulting in systemic inflammation. The immune system’s self-attack via autoreactive B and T immune cells and autoantibodies—antibodies against body’s own proteins—may present as mild to severe symptoms, ranging from fever and body pain to skin allergies and digestive disorders.