Gut microbial metabolism of L-carnitine, leading to the production of trimethylamine N-oxide (TMAO), links red meat consumption to cardiovascular risks. Microbial genes, including cntA/B, the cai operon, and the gbu gene cluster, have been implicated in converting L-carnitine into TMA(O). However, the key genes and microbes remain underexplored.
Leave A Comment