A ‘Trojan horse’ approach may enable development of new antimalarial drugs

Antimalarial drug resistance is a pressing issue in combating the spread of malaria worldwide. In a new study, researchers from Children’s Hospital of Philadelphia (CHOP) have discovered a key process where malarial parasites take up a human blood cell enzyme, which could provide a new approach for antimalarial treatment. The findings, published in the journal Proceedings of the National Academy of Sciences, provide new insights into how to design drugs that more effectively treat patients affected by this devastating infectious disease.

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