Researchers identify a gene to guide novel therapeutics of nonalcoholic fatty liver diseases

Investigators have found that the gene Asah1 plays a crucial protective role in preventing the progression of nonalcoholic fatty liver diseases (NAFLD) into more severe forms of liver disease by regulating hepatic lipid homeostasis and cellular maintenance processes. The findings from the new study, published in The American Journal of Pathology, have the potential to inform new therapeutic strategies and improve outcomes for NAFLD patients.