Axolotls help reveal keratinocytes, not fibroblasts, make collagen for healthy skin

The skin consists of two primary layers. The epidermis, the outermost layer, is predominantly made up of keratinocytes, while the deeper dermis contains blood vessels, nerves, and structural proteins such as collagen, which give the skin its strength and texture. Traditionally, fibroblasts—specialized supporting cells within the dermis—have been believed to play a key role in producing collagen.

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