Common anticancer drugs may offer new hope to PTEN Hamartoma Tumor Syndrome patients

During development, cells grow, expand, and migrate to generate tissues and organs in a highly controlled manner. Many intracellular pathways—series of signaling cascades within a cell—regulate these actions to avoid non-programmed growth that could lead to malformations or cancer. One of these pathways is the PTEN / PI3K axis, a complex series of perfectly balanced chemical reactions.