Patients who have a stent implanted to open a blocked coronary artery face dual risks of developing blood clots and of having excessive bleeding in the months following the procedure. While routine treatment with aspirin plus a second anti-clotting drug, known as dual antiplatelet therapy (DAPT), can prevent blood clots, these drugs may increase risk for bleeding, especially among patients who are older or in poorer health. For patients at either high or low risk of bleeding, the optimal duration of treatment to prevent blood clots without increasing bleeding risk following stent implantation has not been clear.
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