Stem cell infusion timing can prevent acute graft-versus-host disease

A research team has identified the impact of stem cell infusion timing on the incidence and severity of acute graft-versus-host disease (aGVHD) in allogeneic hematopoietic stem cell transplantation (allo-HSCT), highlighting the role of the recipient’s circadian rhythms. The team was led by Prof. Zhan Cheng from the University of Science and Technology of China (USTC) of the Chinese Academy of Sciences and Chief Physician Zhu Xiaoyu from the Department of Hematology at the First Affiliated Hospital of the University of Science and Technology of China.