HLA-DRB1 molecule offers potential target for CAR therapy in relapsed acute myeloid leukemia post-transplantation

One main goal of anti-cancer therapies is to kill tumor cells without affecting the surrounding normal cells. Therefore, many drugs are designed to target tumor-specific antigens, which are molecules only expressed by cancer cells. However, it has proven difficult to identify such specific antigens in certain cancer types, including acute myeloid leukemia (AML).

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