Head-mounted microscope reveals high-resolution neurovascular dynamics in freely behaving mice

In a study published in Science Advances, a research team led by Prof. Liu Chengbo from the Shenzhen Institutes of Advanced Technology (SIAT) of the Chinese Academy of Sciences developed a 1.7-gram head-mounted microscope. This innovative device can simultaneously capture neural activity and cerebral hemodynamics in freely moving mice, providing a novel tool for exploring neurovascular coupling (NVC) in the brain and studying neurological disorders.