Methotrexate as effective as prednisone in pulmonary sarcoidosis, research finds

Prednisone is recommended as the first-line treatment for pulmonary sarcoidosis, but this steroid causes a number of unwanted side effects. Now new research, published at the ATS 2025 International Conference and in the American Journal of Respiratory and Critical Care Medicine, finds that methotrexate provides a comparable alternative.

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