Key protein enables ‘shock and kill’ strategy for HIV latent virus clearance

More than 40 million people worldwide are living with HIV-1, which continues to be a major global health challenge due to its ability to persist silently within immune cells, evading complete eradication. Researchers at LKS Faculty of Medicine, the University of Hong Kong (HKUMed), have identified a specific gene transcription factor, BRD9, as a potential key to unlocking the mechanisms behind HIV-1 latency.