Human norovirus GII.4 exploits unexpected entry mechanism to cause gastroenteritis

Human noroviruses are the leading cause of acute gastroenteritis worldwide, a major global health problem for which there are no specific treatments or vaccines. Understanding the first phase of infection—the process the virus follows to invade cells—is a decisive step in the development of effective preventive and therapeutic strategies. A team led by researchers at Baylor College of Medicine is making strides in that direction.