Innovative double-layer polysaccharide hydrogel shows promise for intestine-targeted oral delivery of probiotics

A research team led by Changhu Xue and Xiangzhao Mao from the Ocean University of China has developed a remarkable double-layer polysaccharide hydrogel (DPH) that promises to revolutionize the field of intestine-targeted oral delivery of probiotics. The team’s findings, titled “A Double-Layer Polysaccharide Hydrogel (DPH) for the Enhanced Intestine-Targeted Oral Delivery of Probiotics” and published in Engineering, demonstrate the potential of DPH to enhance the bioavailability, intestinal colonization, and overall effectiveness of probiotics in treating various diseases.