How your blood vessels tolerate high blood pressure

A research group at Lund University has studied how a molecular sensor located in the blood vessel wall, controls how the vessel compensates for high blood pressure. As we age, the sensor deteriorates, which can worsen vascular damage caused by high blood pressure and consequently lead to secondary diseases affecting the heart, brain, or other organs. In mice, the researchers demonstrate that the absence of the sensor leads to the development of aortic aneurysms. Several key findings have also been confirmed in human blood vessels.