Epidemiology and genetics of clonal hematopoiesis, a premalignant hematopoietic stem cell condition

A comprehensive new study from deCODE genetics published in Nature Genetics, provides insights into the epidemiology and somatic and germline genetics of clonal hematopoiesis. Whole genome sequence data from Iceland and the UK Biobank, combined with a unique somatic mutation Barcoding strategy, was used to investigate clonal hematopoiesis at the population scale.