Mutations in tumor cells discovered to be frequently associated with DNA–RNA hybrids

A study by the University of Seville, CABIMER and IRB Barcelona led by the researchers Andrés Aguilera (US-CABIMER) and Aleix Bayona Feliu (IRB Barcelona) raises the possibility that DNA–RNA hybrids and the mutations in various cellular factors that form them may be responsible for the emergence of carcinogenic processes. The authors therefore stress the need to study these factors to understand and assess possible cancer risks.