Novel insights into HBV-hepatocellular carcinoma at single-cell sequencing

HBV-related HCC poses a significant global health challenge, characterized by its cellular diversity and complex tumor immune microenvironment. The increasing unmet need in HBV-HCC treatment highlights the need for a deeper understanding of the role of the intricate immune microenvironment, tumor cell plasticity, and dynamics of tumor evolution in HBV-associated hepatic carcinogenesis.