Validation of a therapy that overcomes chemotherapy resistance in colon and rectal cancer

A multidisciplinary team made up of doctors and scientists from the Hospital del Mar Medical Research Institute (IMIM-Hospital del Mar) and the Institute for Research in Biomedicine (IRB Barcelona) has led a study, recently published in the Journal of Medicinal Chemistry, that proposes a therapeutic approach for preventing the development of resistance to chemotherapy with oxaliplatin, one of the standard treatments for colon and rectal cancer. The work, which also involved doctors from the Pathological Anatomy and Medical Oncology departments at Hospital del Mar, as well as researchers from the University of Oviedo and the CIBER on Cancer (CIBERONC), is another step toward personalizing the therapeutic approach to cancer.