Study reveals activity of navtemadlin in glioblastoma, points to possible treatment improvements

Glioblastoma is the most aggressive and most common malignant brain cancer in adults. It is currently treated with surgery, followed by radiation and chemotherapy. The prognosis is poor even with treatment. A challenge in conducting clinical trials in brain cancer is that it can be difficult to detect the cellular effects of new agents, as investigators are often limited to using imaging data and patient symptoms.

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