Diesel exhaust exposure leads to disarray in liver function in mice; could also indicate health issues for humans

UCLA Health researchers have discovered significant changes in liver function following exposure to diesel exhaust (DE) in a controlled study involving mice. The study identified disrupted activity in 658 genes and 118 metabolites. These changes led to a higher production of triglycerides, fatty acids, and sugars, largely due to problems with mitochondria, an organelle in the cell responsible for energy production.