Beyond blame: The role of malfunctioning fat tissue in the disease of obesity

Many people who have struggled with their weight have been told to “eat less and move more.” Others have spent years juggling trendy diets, from keto to fasting, with minimal results. Despite their best efforts, what they often hear from physicians, friends, family and even strangers, is that they lack discipline. However, for many people with obesity, their bodies are fighting against them—a battle dictated by biological mechanisms beyond sheer willpower.