Fluorescent sensors reveal dopamine signals in primate brains

Most people are familiar with Pavlovian conditioning, in which a reward-anticipatory behavior follows a reward-predicting stimulus. Behind this mechanism is dopamine released within the striatum, the largest structure of the subcortical basal ganglia, which links motor movements and motivation. Yet it remains unclear exactly what kind of dopamine signal is transmitted to the striatum to cause this behavior in primates.

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