Discovery of Exportin-1’s role in gene expression could impact leukemia treatment

Researchers from Northwestern University have stumbled upon a previously unobserved function of a protein found in the cell nuclei of all flora and fauna. In addition to exporting materials out of the nucleus, the protein, called Exportin-1 (also called Xpo1 or Crm1), seems to play a role in promoting gene transcription, the process that creates RNA replicas of strands of DNA to express genes.