Dopamine neurons that fuel overeating may weaken effectiveness of obesity medication

Delicious and extremely palatable food can increase the tendency of hedonic eating, where one consumes food for the sole purpose of deriving pleasure instead of the body’s energy needs. Hedonic eating often leads to eating beyond satiety (fullness), which is linked to obesity. Although food palatability is closely linked to hedonic eating, the neural mechanisms underlying this process remain largely unclear.

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