Researchers discover pathway critical for lymphoma development

MYC proteins are important regulators of cancer cell growth, proliferation and metabolism through their ability to increase the expression of proteins involved in these processes. Deregulation of MYC proteins occurs in more than half of all cancers and is associated with poor patient prognosis and outcomes. Numerous researchers have devoted significant efforts to try to target MYC proteins as a therapeutic approach to treat cancer. However, this has been extremely challenging to date, and other complementary strategies are being investigated.

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